In addition to overexpression of PPP2R1A, PPP2R1A mutations have been found in different cancer types (Table 2), including ovarian carcinoma, endometrial carcinoma, breast invasive carcinoma, colorectal adenocarcinoma, lung adenocarcinoma, and renal clear cell carcinoma based on cBio Portal for Cancer Genomics (www.cbioportal.org). The gene discussed is PPP2R1A; the disease is invasive breast carcinoma.