Interestingly, we found in-frame deletion pDM in two cancer genes WRN (c2305-2307; ACTAAAGAA > ACTAAA, pK506-E507 deletion, REDACT score: RED*cT) and CBL (c1506-1508; AATTATGAT > AATTAT, pY455-D456 deletion, REDACT score: REd*cT) in pancreatic adenocarcinoma (PAAD). This evidence concerns the gene CBL and cancer.