DHCR7-DT and Increased total eosinophil count: To confirm the crosstalk between NK cells and eosinophils in CRS, we depleted NK cells by anti-ASGM1 treatment in an eosinophilic CRS mouse model created by a combination of Aspergillus protease (AP) and ovalbumin (OVA) and evaluated the change in blood eosinophilia and tissue eosinophilic inflammation.