To this day, several serum markers have been well evaluated in diagnosing liver cirrhosis, including FibroTest, Aspartate aminotransferase-to-Platelet Ratio Index (APRI), the prothrombin index (PI), aspartate aminotransferase (AST) to alanine aminotransferase (ALT) ratio (AAR), the Lok index and the Goteborg University cirrhosis index (GUCI) [14,15]. The gene discussed is GPT; the disease is cirrhosis of liver.