The authors showed that IL-24 suppressed β-GP-induced apoptosis of VSMCs and inhibited the expression of calcification and osteoblast markers by downregulating Bone morphogenic protein- 2 (BMP-2) and the Wnt/β-catenin pathway, which is important in the pathogenesis of both atherosclerosis and cancer. The gene discussed is IL24; the disease is atherosclerosis.