A decrease in GFAP in the orbitofrontal cortex was also observed.71 The authors proposed that the increase in prefrontal cortex was due to medication use whereas the decrease in the orbitofrontal cortex was due to the disease.71 Markova et al.72 reported increased GFAP positive cell area and reduced anisotropy, indicating gliosis, in the olfactory tubercle in schizophrenia. The gene discussed is GFAP; the disease is schizophrenia.