A total of 43 relevant studies with the FCGR2A rs1801274 polymorphism and autoimmune diseases were identified through PubMed and Web of Science search, and 17 articles included KD [6, 16–21], UC [9, 10, 22, 23], CD [7, 10, 22, 24], ATD [8], RA [7, 25], T1D [7] and SLE [26, 27] met the inclusion criteria for analysis. This evidence concerns the gene FCGR2A and systemic lupus erythematosus.