We observed a significant decrease in the levels of CD19+ CD24highCD38high Bregs in DM patients compared to those in healthy controls (0.713 ± 0.275% vs 4.196 ± 0.347%, p < 0.0001) and to those in diseased controls (0.713 ± 0.275% vs 4.010 ± 0.566%, p < 0.0001). Here, CD19 is linked to dermatomyositis.