POMC and focal segmental glomerulosclerosis: Moreover, the anti-proteinuric effect of ACTH seems not limited to a particular type of glomerular disease, but observed in diverse glomerulopathies, including membranous nephropathy (MN)16, 18, 19, 21, 22, minimal change disease (MCD)18, 19, 21, focal segmental glomerulosclerosis (FSGS)18, 19, 20, 21, 23 and IgA nephropathy19, implying that the melanocortin effect might, at least in part, target a pathogenic pathway common to all proteinuric kidney diseases.