EIF3B and esophageal squamous cell carcinoma: We applied CCK-8 and colony-forming assay to study the proliferative change after knockdown of EIF3B and found that, compared with the normal control (NC) groups, both two cell lines with knockdown of EIF3B showed low proliferative ability, which indicated that EIF3B promoted the proliferation of ESCC (Figure 2C and 2D).