CXCL8 and neoplasm: Interestingly, when mice were inoculated with T/H/H-HepG2 or T/H/H-MCF-7 cells, 14,15-EET-treatment increased the levels of human IL8 mRNA, but not mouse Cxcl15 mRNA in the lung tissues (Figure 3B), suggesting that 14,15-EET induced hIL-8/mCXCL15 expression in tumor cells, but not non-cancerous cells.