Five genes (TP53, BAI1, THSD1, ARID2, and KIAA2022) verified in our study were also mutated at a frequency greater than 5%in gastric adenocarcinoma in the COSMIC database, but the amino acid changes F567L in ARID2, D76E in BAI1, L21I in THSD1, and D955H in KIAA2022 had not been reported previously in gastric cancer. The gene discussed is TP53; the disease is gastric cancer.