Moreover, overexpression of L1CAM in U-118 MG GBM cells (L1LE) [28] promoted the binding of GBM cells to ECs as compared to U-118 MG cells expressing the vector control (Figure 1H) and the expression of L1CAM on the 08387 CSCs promoted increased binding of CSCs to ECs as compared to the paired 08387 non-stem tumor cells (NSTCs) (SFigure 1B). Here, L1CAM is linked to neoplasm.