LN-308 GBM cells were utilized as they express L1CAM when propagated as neurospheres in NBM (Figure 7A), bind to ECs in the cell-cell adhesion assay in an L1CAM-dependent manner (Figure 7B), and promote EC migration towards bFGF in an L1CAM-dependent manner (Figure 7C&7D). Here, L1CAM is linked to glioblastoma.