In previous studies, miR-10a inhibited epithelial-to-mesenchymal transformation (EMT), apoptosis and autophagy, induced chemo-resistance, invasion, proliferation, and tumor growth thought suppressing different protein such as EphA8, BCL2L11, TFAP2C, CDKN1A, p21, and p16 [17, 18]. Here, CDKN1A is linked to neoplasm.