Although allele A of the FCGR2A gene (rs1801274) has recently been associated with greater susceptibility to severe forms of infection with influenza A(H1N1)pdm09 in the Mexican population in which the Amerindian contribution is high (approximately 60 %) [14], the present study found no association of this polymorphism with more severe influenza infection in the Brazilian admixed population. This evidence concerns the gene FCGR2A and influenza.