Knockdown of ATB reduced the expression of TGF-β2 at mRNA and protein levels, and sh-ATB combined with miR-200a mimics significantly reduced the expression levels of TGF-β2, in contrast, miR-200a inhibitors restored the reduction of TGF-β2 expression in ATB knockdown glioma cells (Fig. 7a-c). The gene discussed is TGFB2; the disease is glioma.