SPSB1 and malignant colon neoplasm: Among the 14 CNVs identified by the SNP array, four involved genes (SPSB1, CTNNA3, IGHG1, and CRFL2) have been implicated in tumorigenesis, however, other than in colon cancer, thus only one rearrangement, a duplication of the chromosomal region 22q11.22, may be of interest and relevant to this study.