As listed in Table 4, the FPRP test results revealed that all 4 gene models (AA + AG vs. GG, AA vs. GG, AG vs. GG, A vs. G) of the SDF-1 rs1801157 gene polymorphism were truly associated with cancer risk (FPRP = 0.011, 0.001, 0.008, 0.017, respectively) at an a priori probability level of 0.001 with an OR of 1.5, especially in Asians. This evidence concerns the gene CXCL12 and cancer.