However, both kinds of engrafted cells insufficiently generated APs 4 and 6 weeks after transplantation in the DG of AD mouse (Fig. 6a; Control-NSCs n = 5 from 3 mice, BDNF-NSCs n = 5 from 3 mice) and revealed immature granule cell properties (input resistance > 1 GΩ). The gene discussed is BDNF; the disease is Alzheimer disease.