In DSS- or TNBS-induced colitis animal models, BPB strains, such as F. prausnitzii, Butyricicoccus pullicaecorum, Clostridium butyricum and Eubacterium limosum, have been shown to inhibit myeloperoxidase (MPO) activity and decrease levels of TNF-α and IL-12 in the colon20, 21, 22, 23. This evidence concerns the gene MPO and colitis.