Late genes also include human disease genes such as BATF2 (acute stress disorder), GJB6 (sensorineural deafness and a variety of skin disorders) or APOE (lipoproteinemias), as well as a variety of biological functions such as cell adhesion (NDNF and THBS1), ribonucleotide binding (NABP1 and MSH3) or interaction with various organelles (FKBP4 and MARS2). This evidence concerns the gene MSH3 and skin disorder.