PDIK1L and Familial advanced sleep-phase syndrome: Casein kinase mutations also lead to Drosophiladoubletime (Kloss et al. 1998; Price et al. 1998) and human familial advanced sleep phase syndrome (FASPS) (Xu et al. 2005), and are a key element in the circadian system of zebrafish (Smadja Storz et al. 2013).