Additionally, Nox1 expression was also found in neurons (Additional file 3: Figure S3), as we have previously showed that Nox1 is upregulated on neurons in response to other in vivo injury paradigms such as ischemia or paraquat and 6-hydroxydopamine (6-OHDA)-mediated neuronal death [34, 67, 68]. This evidence concerns the gene NOX1 and ischemia.