RNF8 and cancer: Of the 36 cases examined, 18 (50.0 %) showed significant higher expression of RNF8 in the cancerous tissues when compared with the corresponding adjacent normal tissues; while another 16 (44.4 %) showed similar level of expression in both tissues; only 2 (5.6 %) displayed a reverse expression pattern, in which RNF8 expression was lower in the cancer tissues than that of normal adjacent ones.