NPPB and pulmonary embolism: Many prognostic indicators have been developed for PE, such as the simplified pulmonary embolism severity index (sPESI), brain natriuretic peptide (BNP), N-terminal pro-Brain Natriuretic Peptide (NT-pro-BNP), indications of right ventricular dysfunction, heart-type fatty acid-binding protein, and troponin concentrations.