They identified four new CRC risk variants at 14q22.2 (rs4444235, bone morphogenetic protein 4 (BMP4); P = 8.10E-10), 16q22.1 (rs9929218, cadherin 1 (CDH1); P = 1.20E-8), 19q13.1 (rrs9929218, rhophilin, Rho GTPase binding protein 2 (RHPN2); P = 4.60E-09) and 20p12.3 (rs961253; P = 2.00E-10) [16]. Here, CDH1 is linked to colorectal carcinoma.