For instance, lncRNA-hPVT1, by binding to the RNA-binding protein NOP2, was found to increase NOP2 levels by enhancing the stability of NOP2 proteins and hence promote carcinogenesis, cell proliferation, and stem cell-like properties in hepatocellular carcinoma cells depending on the presence of NOP2 [19]. This evidence concerns the gene NOP2 and hepatocellular carcinoma.