MKI67 and small cell lung carcinoma: As can be seen from the boxplots of Figure 2 and as confirmed by the Mann-Whitney-Test, Ki-67 protein levels increased highly significantly from TC to AC (Ki-67-Average: U = −4.337, p < 0.001, Ki-67-Hotspots: U = −5.041, p < 0.001; Ki-67-FADIA: U = −2.639, p = 0.008) and from AC to SCLC/LCNEC (Ki-67-Average: U = −6.592, p < 0.001/U = −3.913, p < 0.001, Ki-67-Hotspots: U = −6.277, p < 0.001/U = −3.921, p < 0.001; Ki-67-FADIA: U = −5.903, p < 0.001/U = −3.900, p < 0.001) in all three evaluation systems.