TP53 and cancer: It is worth noting that it has recently been demonstrated that Fallopian tube secretory cell expansion and the ratio between secretory/ciliated cells (S/C ratio) are linked to pelvic serous neoplasia [91] and in this scenario the cancer cells of the serous tubal intraepithelial carcinoma (STIC) bearing a “p53 signature” invade onto the ovary and implant on peritoneal surfaces [92–94].