To explore the context dependent role of Rab25 in breast cancer subtypes, we created stable lines with exogenously manipulated levels of Rab25 in a luminal B background (such as MCF7, T47D) as well as in basal (MCF10A) or claudin-low background (MDA231) (Supplementary Figure S1C). This evidence concerns the gene RAB25 and breast carcinoma.