In addition to the proteins that are known to be expressed by PSCs, results showed the expression of certain other proteins such as macrophage migration inhibitory factors (MIFs) and galectin-3 (Supplementary Table S3; Figure 3D), which are known to promote the progression of PC but have not been reported to be expressed by PSCs [26, 27]. The gene discussed is MIF; the disease is pachyonychia congenita.