MSLN and Miyoshi myopathy: This finding, and the report that a combination of circulating miRNAs rather than a single miRNA biomarker increased early diagnostic performance [165], suggest that an MM-multimarker signature including miR-126-3p, miR-103a-3p, miR-625-3p, and mesothelin would maximize the effectiveness of asbestos-exposed patient monitoring for early detection of the switch to carcinogenesis.