In other hematological cancers, CX3CR1 and its ligand, CX3CL1, have been proposed to be involved in the interaction between chronic lymphocytic leukemia cells and their microenvironment,30 and CCR1 has a crucial role in the pathogenesis of myeloma-associated bone disease. Here, CX3CR1 is linked to hematopoietic and lymphoid cell neoplasm.