TGFB1 and Familial prostate cancer: For example, chemokine ligand 17 (CCL17), promotes the stemness, EMT process, the TGF-β1 and Wnt/β-catenin signaling in MHCC97L cells[45]; chemokine (C-X3-C motif) ligand 1 (CX3CL1), participates in the molecular events that regulate cell adhesion, migration and survival of human prostate cancer cells[46].