TP53 and lung adenocarcinoma: For instance, Lnc_bc060912 were proved to be regulated by p53 [92], and to suppress cell apoptosis via interacting with the two DNA damage repair proteins PARP1 and NPM1 [92], while MEG3 can regulate cisplatin resistance through controlling the expression of p53 and Bcl-xl in lung adenocarcinoma cells [93].