Among different molecular subtypes, germline BRCA1/2 P/LP variants were preferentially detected in the patients with triple-negative (14/70; 20.0%) and Luminal B (21/290; 7.2%) breast cancer, as compared to the patients of Luminal A (1/60; 1.7%) and HER2 positive (1/67; 1.5%). The gene discussed is BRCA1; the disease is breast cancer.