For example, EIF2AK2 [16], IFI27 [16,17], OAS1[18–23], OAS2[21,23,24], PLSCR1[16] and STAT1[25–27] were up-regulated in SLE patients vs. controls.Specifically, up-regulation of IFI27 and IFI44L in SLE patients was further observed in the synovial tissue[26]. This evidence concerns the gene IFI44L and systemic lupus erythematosus.