Spanning ~200KB, this chromosomal region contains three regulatory protein coding genes—BUD13, ZPR1 and SIK3—and four apolipoprotein coding genes—APOA1, APOC3, APOA4 and APOA5. In the present study, we made an attempt to explore the association pattern of 96 prioritized SNPs of the 11q23.3 region with CAD in the population of Hyderabad, India. This evidence concerns the gene APOC3 and coronary artery disorder.