Furthermore, in agreement with the activity of neurons being controlled by external calcium concentration, is the finding that CaSR is expressed in neurons in hippocampus (Mudò et al., 2009; Kim et al., 2014; Bai et al., 2015; Dong et al., 2015), cerebellum (Kapoor et al., 2008), cortex (Kapoor et al., 2008; Phillips et al., 2008; Vyleta and Smith, 2011), striatum after experimentally induced stroke (Noh et al., 2015), and sensory neurons (Vysotskaya et al., 2014). Here, CASR is linked to Stroke.