CRP and rheumatoid arthritis: Based on the data showing that baseline miR-125b expression is higher in responders than in non-responders at 3 months, we performed ROC curve analysis to determine the predictive value of baseline miR-125b expression and conventional baseline parameters of disease activity, including DAS28, CRP levels and ESR, in separating patients with early RA who achieve an optimal treatment outcome (remission or low disease activity) from those who do not have such a response.