A cutoff value of serum CXCL3 (66.36 pg/ml), which was of a sensitivity of 62.4% and a specificity of 88.1% (Fig. 5d, Area Under Curve is 0.826 ± 0.029, with the 95% CI of 0.770 to 0.882), was used to divide 125 HCC patients into two groups: 47 (37.6%) patients in the low CXCL3 expression group, and 78 (62.4%) patients in the high CXCL3 expression group. The gene discussed is CXCL3; the disease is hepatocellular carcinoma.