Correlation analysis (Pearson correlation) was performed to analyse the association of CD147 and MMP-2 expression with known prognostic factors, vasculogenic mimicry (VM), the mature vasculature (von Willebrand Factor) and tumor induced angiogenesis (by means of Endoglin expression).<h4>Results</h4>CD147 and MMP-2 were expressed in 47 (96.0 %) of the uveal melanomas. This evidence concerns the gene MMP2 and neoplasm.