24, 25, 26 Cd first accumulates in the liver after exposure.27 Most of the Cd is captured by MT proteins to form Cd/MT complexes that are gradually released into the blood and reabsorbed from the glomerular filtrate in the kidney.27 Then, the complexes degrade quickly to release the Cd, leading to renal injury.28 Our study showed that Cd exposure resulted in hepatomegaly, which was consistent with previous studies.29, 30mMTs mRNA was induced by Cd both in livers and kidneys, which indicated that Cd had been transferred and released into the kidney which might result in renal damage. Here, MCAT is linked to injury.