Fully activated and matured DCs can migrate to secondary lymphoid organs and activate antigen-specific naive T lymphocyte in an efficient manner.2 In our hands, melanoma cells treated with various doses of P2Et did promote phagocytosis, probably involving CRT as an ‘eat-me' signal, and cross priming of bone marrow-derived dendritic cells, which was indirectly evidenced by the in vivo generation of IFN-γ producing, Trp2-specific CD8+T cells. Here, CALR is linked to melanoma.