Although a second module of 26 genes in neutrophils also correlated well with a diagnosis of SLE (figure 1B), it did not correlate well with the curated IFN-1 score (Spearman r=0.23) and only contained genes suggestive of broader cellular activation (ie, FOS, JUN, CCL3, CCL4, CXCL1, CXCL8, PTGS2). This evidence concerns the gene FOS and systemic lupus erythematosus.