IFNG and coronary artery disorder: Implication of anti-inflammatory mediators in treatment of ischemic heart failure has been reported.26,27 So, positive effect of propranolol on treatment of many cardiovascular problems such as ischemic heart diseases and heart malfunction 12,13 may be in part owing to its anti-inflammatory effects through inhibition of inflammatory cytokines (IL-2 and IFN-γ) was shown in this study.