The results of the present study provides a clue on the relevance of HLA-DP rs3077, HLA-DQ rs3920, and ICAM-1 rs1437 variants in ovarian cancer, as some alleles were identified to be linked with ovarian cancer as HLA-DP rs3077 AA, HLA-DQ rs3920 GG, ICAM-1 rs1437 CC, and CT genotypes (OR = 43.5, 6, 25, and 2.6, respectively). The gene discussed is ICAM1; the disease is ovarian carcinoma.