Previous studies demonstrated that MWCNT can be inducers of lung fibrogenesis suggesting several molecular mechanisms: MWCNT can stimulate oxidative stress and mitochondrial damage in lung cells [60, 61], activate nuclear factor-κB signalling to boost inflammatory and pro-fibrogenic factors secretion [6, 8, 10, 50], and finally promote lung fibrosis through EMT via the TGF-β/Smad signalling [10, 19, 22]. This evidence concerns the gene TGFB1 and pulmonary fibrosis.