SFTPA1 and chronic lung disease: Genetic studies have been conducted in human populations of adults, children, and newborns, where single nucleotide polymorphisms, haplotypes, and other genetic variants of SP-A1 and SP-A2 genes have been associated with acute and chronic lung diseases, like cystic fibrosis, asthma, allergic rhinitis, and chronic obstructive pulmonary disease [6].