Ribas et al. also found that AR could directly bind to miR-21 promoter to exert its influence on the prostate cancer growth57, and Murata et al. reported that miR-148a was an androgen-responsive miRNA that could promote prostate LNCaP cell growth via repressing its target CAND1 expression58. The gene discussed is CAND1; the disease is Familial prostate cancer.